8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsSat, Dec 5th 2026
ReturnsSun, Dec 13th 2026
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Mississippi River, Oak Alley, New Orleans
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate… 
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsThu, Dec 10th 2026
ReturnsFri, Dec 18th 2026
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
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Ocean View
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsWed, Dec 16th 2026
ReturnsThu, Dec 24th 2026
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
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Ocean View
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Balcony
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Suite
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7 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsMon, Dec 21st 2026
ReturnsMon, Dec 28th 2026
Nights7
Departing PortNew Orleans
Ports of CallNew Orleans, Gulfport, Biloxi (2 Days), Ocean Springs, MS, Mobile, Pensacola (2 Days)
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
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Ocean View
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsTue, Dec 22nd 2026
ReturnsWed, Dec 30th 2026
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Cruising the River, St. Francisville, Natchez, Vicksburg, Cleveland, Mississippi River, Memphis
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
Call for pricing
Ocean View
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Balcony
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Suite
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7 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Melody
DepartsSun, Dec 27th 2026
ReturnsSun, Jan 3rd 2027
Nights7
Departing PortPensacola
Ports of CallPensacola, Mobile, Gulfport, Biloxi, Ocean Springs, MS, Gulfport, Biloxi, New Orleans (2 Days)
American Cruise Lines is pleased to announce the newest ship in our revolutionary series of modern riverboat series. American Melody will begin its inaugural season on the Mississippi River in the summer of 2021 and was specifically designed to navigate…
Inside Cabin
Call for pricing
Ocean View
Call for pricing
Balcony
Call for pricing
Suite
Call for pricing
Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
